To raise awareness and understanding of the rare disease Moyamoya;
To provide support and resourcing in terms of information to Moyamoya Disease patients and their families;
To work towards providing limited financial assistance on a single payment basis to patients of Moyamoya Disease or their primary carer.
National Rehabilitation Information Center (NARIC)
8201 Corporate Drive, Suite 600 Landover, MD 20785
301-459-5900, 301-459-5984 (TTY)800-346-2742
National Organization for Rare Disorders (NORD)
P.O. Box 1968 (55 Kenosia Avenue) Danbury, CT 06813-1968
203-744-0100 Voice Mail 800-999-NORD (6673)
What is moyamoya disease?
Moyamoya disease is a rare, progressive cerebrovascular disorder caused by blocked arteries at the base of the brain in an area called the basal ganglia.
The name “moyamoya” means “puff of smoke” in Japanese and describes the look of the tangle of tiny vessels formed to compensate for the blockage. Moyamoya disease was first described in Japan in the 1960’s and it has since been found in individuals in the United States, Europe, Australia, and Africa.
The disease primarily affects children, but it can also occur in adults. In children, the first symptom of Moyamoya disease is often stroke, or recurrent transient ischaemic attacks (TIA, commonly referred to as “mini-strokes”), frequently accompanied by muscular weakness or paralysis affecting one side of the body, or seizures.
Adults most often experience a hemorrhagic stroke due to recurring blood clots in the affected brain vessels. Individuals with this disorder may have disturbed consciousness,speech deficits (usually aphasia), sensory and cognitive impairments, involuntary movements, and vision problems.
Because it tends to run in families, researchers think that Moyamoya disease is the result of inherited genetic abnormalities. Studies that look for the abnormal gene(s) may help reveal the bio mechanisms that cause the disorder.
Is there any treatment?
There are several types of revascularization surgery that can restore blood flow to the brain by opening narrowed blood vessels or by bypassing blocked arteries. Children usually respond better to revascularization surgery than adults, but the majority of individuals have no further strokes or related problems after surgery.
What is the prognosis?
Without surgery, the majority of individuals with Moyamoya disease will experience mental decline and multiple strokes because of the progressive narrowing of arteries. Without treatment, Moyamoya disease can be fatal as the result of intracerebral haemorrhage.
What research is being done?
The NINDS conducts neurological research inlaboratories at the NIH and also supports additional research throughgrants to major medical institutions across the country. These studies,which range from clinical trials to investigations of basic biological mechanisms,are aimed at discovering how and why diseases develop in the brain, and focuson finding ways to prevent, treat, or cure them.
What is Adventure All Stars?
Follow our team of adventurers as they raise money for
Moyamoya Australia, then head off on the trip of a lifetime.